Frequently Asked Questions

There are other products on the market which contain EGF cellular activator, however BIOEFFECT's groundbreaking serum is the first skin care product to contain EGF made in plants. Other products contain EGF grown in E.coli bacteria or animal cells, whereas production of EGF in barley ensures that the EGF is void of bacterial endotoxins, human infectious agents and other potential contaminations associated with conventional production hosts.

No, BIOEFFECT‘s 30 DAY TREATMENT contains three cellular activators EGF, KGF and IL-1a that work in synergy on the two decisive layers of the skin, the epidermis and dermis. BIOEFFECT is committed to continued research on the efficacy of cellular activators in cosmetics.

The cellular activators in BIOEFFECT products are unlike all other growth factors on the market because they are plant-made. To date, all other companies that use cellular activators in their skin care products use proteins produced in bacteria (E. coli), animal cells or yeast. Production of cellular activators in barley seeds ensures they are void of bacterial endotoxins, human infectious agents and other potential contaminations associated with production in conventional production hosts. By producing the cellular activators in plants, it is possible to achieve an unparalleled level of purity and activity.

The unique biotechnology behind BIOEFFECT is based on our understanding of the genetic language, the DNA code: we have translated the genetic instructions on how EGF is made in humans, into the genetic dialect that the barley plant understand. A laboratory-synthesized gene that codes for a human-like EGF is transferred into the barley. This synthesized gene instructs the barley to make the EGF only in its seeds. The barley produced EGF protein (i.e. Barley sh-Oligopeptide-1) is identical, or replica of the EGF protein found in our skin and, therefore, our skin cells understand it as its own. However, using this technology NO human gene, or DNA, is cloned into the barley plant, just a synthetic DNA code that the barley plant can understand.

As our EGF-producing barley plant has a new DNA code, compared to the native barley, it is called a genetically modified organism(GMO), or bioengineered barley plant. This innovative, green biotechnology that BIOEFFECT has developed is the key to production of the purest form of growth factor, including the EGF cellular activator used in BIOEFFECT. The technology platform is based on using the bioengineered, or genetically modified barley seed as a host for production of proteins to be used in skin care products.

No. Proteins that are produced in genetically modified organisms are just like other proteins and can be an exact replica of their natural form with the same amino acids and same form, such as the EGF in BIOEFFECT. Without the GMO, or bioengineering technology, our life would be very difficult as so many important, life saving drugs are produced using genetically modified organisms, such as genetically modified bacteria (E. coli), hamster cells, yeasts or animal cells. Without GMO where would we get our insulin, or the many drugs for treating cancer, autoimmune diseases etc., injected by millions of people all over the world?

The formulation of the BIOEFFECT EGF SERUM was specifically designed to maintain and stimulate the activity of the EGF cellular activator, independent of skin type. Studies reveal that the serum has an equally excellent impact on all types of skin, including even the most sensitive. Furthermore it only contains 7 ingredients and is void of known allergens.

No. BIOEFFECT EGF SERUM is a superlative moisturizer in its own right. It is possible that fatty/oily substances in traditional night creams may reduce the efficacy of the EGF cellular activator, we therefore recommend using EGF alone during the night. However if you would like to use other cream on top the best would be to wait from 10 to 20 minutes before applying next product in your skincare regimen.

It is fine to use make-up over the serum, but we recommend that you wait a least 10 minutes before applying any other product (skincare or make-up).

BIOEFFECT EGF DAY SERUM is an advanced anti-aging serum specifically developed for daytime use as an effective routine along with our bestseller BIOEFFECT EGF SERUM. It delivers  multiple anti-aging benefits, restores the skin’s moisture balance and provides a smooth finish, an ideal base for make-up application.

For younger skin we recommend BIOEFFECTDAYTIME  a nourishing day cream that was developed specifically to work in tandem with BIOEFFECT EGF SERUM and prolong its night-time activity.

For a more intense boost we recommend to kick start your EGF experience with  BIOEFFECT 30 DAY TREATMENT, which should be used in the morning and evening for one month treatment periods one to four months a year, depending on the needs (stage of wrinkle development).

Compliment your EGF regimen with our EGF EYE SERUM  specifically formulated to target the delicate skin of the eye area, with cooling roller applicator to reduce dark circles and puffiness.

We recommend using BIOEFFECT BODYINTENSIVE on the body. BIOEFFECT BODY INTENSIVE has been specially developed to help smooth, soften and firm the appearance of skin on the body. BIOEFFECT EGF SERUM can nevertheless be used on the body, although it was formulated particularly to target the fragile skin of the face, neck and eye contour area.

If the serum is applied on the face and neck once a day, a 15 ml vial should last about three months. Start with 2 drops and increase till 4 if needed. If you experience oily or sticky feeling decrease the dosage (EGF Serum do not contains oils, fragrances or paraben), it means you are applying too much formula on the skin.

Yes. The combined effect of the EGF cellular activator and hyaluronic acid moisturize, nourish and soften the skin. BIOEFFECT EGF SERUM is particularly beneficial for dry and sensitive skin and numerous users have reported that their dry spots diminish as the skin becomes more fully hydrated.

BIOEFECT EGF SERUM contains EGF, a naturally occurring skin protein that can be thought of as the „conductor“ for skin cell renewal. EGF signals skin cells to speed up their renewal process and to increase the production of collagen and elastin, resulting in increased radiance and luminosity and reduction of the appearance of fine lines and wrinkles.

Many users report that the serum‘s hydrating effect means sagging under the eyes is reduced and dark circles dramatically disappear as skin becomes smoother and the complexion more even.

If you are looking for reduction of fine lines and wrinkles, restored radiance and firmness in the eye area, and reduced signs of tiredness we  recommend to use BIOEFFECTEGF EYE MASK TREATMENT. It’s a quick, yet advanced, at-home treatment that complements an EGF routine as it refreshes and rejuvenates the sensitive skin around your eyes.

Although there have been no specific trials on sufferers of eczema or other difficult skin conditions, BIOEFFECT EGF SERUM's commitment to purity means that many such users are rewarded with very positive results.

No preservatives are used in the production of BIOEFFECT EGF SERUM. We pride ourselves in only using those ingredients necessary to deliver the cellular activator in its most effective form.

The warmth felt by some users after applying the BIOEFFECT EGF SERUM is a sign of the increased cell renewing activity taking place within the skin.

A small number of people report the formation of minor pimples when they begin using BIOEFFECT EGF SERUM. This may be due to the highly active ingredients causing increased cellular activity at the epidermis surface. Users normally find the pimples disappear after one or two weeks. If this is not the case please discontinue use and seek further advice.

Like your skin, the activity of proteins such as of the EGF cellular activator, is very sensitive to chemicals. The formulation of BIOEFFECT EGF SERUM is therefore exceptionally pure and it only contains ingredients which protect and enhance the activity of the EGF cellular activator.

• Glycerin - For moisturizing effect.
• Aqua - Pure Icelandic spring water.
• Sodium hyaluronate - The salt of hyaluronic acid. A very moisturizing agent.
• Tromethamine – A natural buffering agent with an effective pH range of 7.0-9.2.
• Sodium chloride - A stabilizer to enhance the effectiveness of the EGF.
• Hordeum vulgare seed extract – Active barley botanical extract.
• EGF (Barley sh-oligopeptide-1) - EGF (Epidermal growth factor), a biologically active protein that stimulates cell renewal.

No. We strive to keep our products as pure as possible so no fragrances are added to the serum.

Due to the general cellular activating properties of EGF we recommend that people who have, or have had, a medical history of skin diseases or other diseases that could potentially affect the skin, should consult their physician before using any "active" skin care product.

The BIOEFFECT EGF SERUM is scientifically developed, responsibly manufactured and contains only pure and safe ingredients. No preservatives, fragrances or colorants are added to the serum. The active ingredient, EGF cellular activator is produced in barley seeds, using gene technology in a green production system in Iceland. The serum is therefore a very pure and organic skin care product, however since gene technology and science form the foundation for the serum's production, it cannot by classified and certified "organic".

Yes, many users prefer to apply the serum on clean skin in the morning and some use it both day and night. It is advisable not to apply make-up or any other product within 10 minutes of using BIOEFFECT EGF SERUM, as it may interfere with the activity of the EGF cellular activator. The serum does not contain any sun protection, we recommend touse a seperate sunscreen to protect from harmful UVA

BIOEFFECT EGF SERUM does not contain any of the ingredients found on lists of skincare substances recommended to be avoided during pregnancy. In addition, all ingredients of BIOEFFECT EGF SERUM are legally permitted as cosmetic ingredients as per EU Directives 76/768/EEC. However, no specific studies have been carried out on using BIOEFFECT EGF SERUM during pregnancy. We recommend pregnant women to consult with their physician before using BIOEFFECT EGF SERUM.

The cellular activators (as well called “growth factors”) work as a natural signalling system between skin cells, effectively “switching on“ cell repair while maintaining the appearance of young and healthy-looking skin. By harnessing the proven anti-aging power of cellular activators, BIOEFFECT skin care products stimulate the skin‘s own renewal process.

The unique biotechnology behind BIOEFFECT is based on our understanding of the genetic language: we have translated the genetic instructions on how EGF cellular activator (Epidermal Growth Factor) is made, into the genetic dialect of barley. That way we can instruct the barley plant to make EGF in its seed, that is identical to the EGF in our skin, and which the skin understands as its own.

EGF stands for Epidermal Growth Factor. Growth factors are cellular activators: they are signal molecules that communicate with cells, sending a message to repair, rejuvenate, or proliferate. Hundreds of different growth factors control the more than 300 cell types in humans. They’re the crucial foremen on the construction site that is your body’s development, and they work at full capacity for years. From birth until adulthood, our bodies manufacture copious amounts of various growth factors that affect the growth of everything from bones to organs to nerves to skin. But when we reach maturity, production diminishes. As a result, cell turnover and repair slows, eventually affecting our health and appearance. In fact, our skin gets thinner by 1% each year after we turn 20, and five years after menopause, our skin becomes 30% thinner.Since 1986, medical research into growth factors has exploded. Huge breakthroughs include life-saving treatments such as the use of G-CSF, a growth factor that induces the production of white blood cells after chemotherapy. EGF, or epidermal growth factor, helps burn victims grow new skin and speed wound recovery. But EGF may also be used to replenish the body’s own supply, which diminishes with age. EGF application stimulates the body’s own skin cells to proliferate, increasing skin turnover and radiance while slowing the aging process. It boosts production of collagen and elastin, the skin’s bouncy scaffolding, increasing tone and elasticity. It boosts the skin’s capacity to store water and reduce water loss. The result is healthier, denser, more hydrated,  younger-looking skin.

Human growth factors are used a lot in medical research, such as in stem cell technology, but some of them are also used as very important cancer drugs.

The significance was tremendous: for medical research, for understanding our cells, for drugs, for stem cell technology research and for the new, regenerative medicine.

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